MMP-2 (Protein|Antibody|cDNA Clone|ELISA Kit)

All MMP-2 reagents are produced in house and quality controlled, including 7 MMP-2 Antibody, 13 MMP-2 Gene, 1 MMP-2 IPKit, 2 MMP-2 Lysate, 2 MMP-2 Protein, 1 MMP-2 qPCR. All MMP-2 reagents are ready to use.

Recombinant MMP-2 proteins are expressed by HEK293 Cells with fusion tags as N-His, Native.

MMP-2antibodies are validated with different applications, which are ELISA, WB, IP.

MMP-2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each MMP-2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

MMP-2 Protein (2)

Species

MMP-2 Protein, Mouse, Recombinant (His Tag)

52740-M07H

Expression host: HEK293 Cells

Mouse MMP2/MMP-2/CLG4A Protein 12188

MMP-2 Protein, Human, Recombinant

10082-HNAH

Expression host: HEK293 Cells

Human MMP2/MMP-2/CLG4A Protein 8374
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MMP-2 Antibody (7)

Application Clonality
Host

Anti-MMP-2 Antibody

10082-MM05

Specificity: Human

Application: WB,ELISA

Clonality: MAb

Human MMP2/MMP-2/CLG4A Western blot (WB) 13113

Anti-MMP-2 Antibody

10082-R026

Specificity: Human

Application: WB

Clonality: MAb

Human MMP2/MMP-2/CLG4A Western blot (WB) 13114

Anti-MMP-2 Antibody

10082-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-MMP-2 Antibody

10082-RP02

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-MMP-2 Antibody

52740-T36

Specificity: Mouse

Application: WB,IP

Clonality: PAb

Mouse MMP2/MMP-2/CLG4A Immunoprecipitation(IP) 6220

Anti-MMP-2 Antibody

10082-R029

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-MMP-2 Antibody

52740-RP01

Specificity: Mouse

Application: ELISA

Clonality: PAb

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MMP-2 cDNA Clone (13)

Human

MMP-2 qPCR Primer (1)

MMP-2 IP Kit (1)

MMP-2 Lysate (2)

Matrix Metalloproteinase-2 (MMP-2) is an enzyme that degrades components of the extracellular matrix and thus plays a pivotal role in cell migration during physiological and pathological processes. MMP-2 expression is dependent on extracellular matrix metalloproteinase inducer (EMMPRIN), Her2/neu, growth factors, cytokines, and hormones. Pro-MMP-2 activation needs MT1-MMP and TIMP-2 contribution. MMP-2 is changed in distribution and increased in amount in the ventral cochlear nucleus after unilateral cochlear ablation. A low level of MMP-2 is linked to favorable prognosis in patients with a hormone receptor-negative tumor, usually associated with high risk. As a zymogen requiring proteolytic activation for catalytic activity, MMP-2 has been implicated broadly in the invasion and metastasis of many cancer model systems, including human breast cancer (HBC). Blocking MMP-2 secretion and activation during breast carcinoma development may decrease metastasis. The detection of active MMP-2 alone or the rate of pro-MMP-2 and active MMP-2 is considered a very sensitive indicator of cancer metastasis. Modulation of MMP-2 expression and activation through specific inhibitors and activators may thus provide a new mechanism for breast cancer treatment.

Protein
Antibody
Gene
qPCR
IPKit
Lysate
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