RANKL (Protein|Antibody|cDNA Clone|ELISA Kit)

All RANKL reagents are produced in house and quality controlled, including 8 RANKL Antibody, 1 RANKL ELISA, 52 RANKL Gene, 1 RANKL IPKit, 6 RANKL Lysate, 6 RANKL Protein, 3 RANKL qPCR. All RANKL reagents are ready to use.

Recombinant RANKL proteins are expressed by HEK293 Cells with fusion tags as N-human IgG1-Fc, N-mouse IgG1-Fc, N-rabbit IgG-Fc, N-cleavage.

RANKLantibodies are validated with different applications, which are Neutralization, ELISA(Cap), ELISA, WB, ELISA(Det), IP.

RANKLcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each RANKL of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

RANKLELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

RANKL Protein (6)

Species

RANKL Protein, Human, Recombinant (Fc Tag)

11682-H01H

Expression host: HEK293 Cells

Human RANKL/OPGL/TNFSF11/CD254 Protein 9701

RANKL Protein, Human, Recombinant (Fc Tag)

11682-H15H

Expression host: HEK293 Cells

Human RANKL/OPGL/TNFSF11/CD254 Protein 9703

RANKL Protein, Cynomolgus, Recombinant (Fc Tag)

90301-C01H

Expression host: HEK293 Cells

Cynomolgus RANKL/OPGL/TNFSF11/CD254 Protein 12954

RANKL Protein, Human, Recombinant

11682-HNCH

Expression host: HEK293 Cells

Human RANKL/OPGL/TNFSF11/CD254 Protein 9704

RANKL Protein, Human, Recombinant (Fc Tag)

11682-H04H

Expression host: HEK293 Cells

Human RANKL/OPGL/TNFSF11/CD254 Protein 9702

RANKL Protein, Mouse, Recombinant (Fc Tag)

50343-M01H

Expression host: HEK293 Cells

Mouse RANKL/OPGL/TNFSF11/CD254 Protein 11585
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RANKL Antibody (8)

Anti-RANKL Antibody

11682-T16

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-RANKL Antibody

11682-R101

Specificity: Human

Application: WB,ELISA,ELISA(Det),IP

Clonality: MAb

Human RANKL/OPGL/TNFSF11/CD254 Western blot (WB) 6644

Anti-RANKL Antibody

11682-R128

Specificity: Human

Application: ELISA(Cap)

Clonality: MAb

Anti-RANKL Antibody

11682-T48

Specificity: Human

Application: WB,ELISA

Clonality: PAb

Human RANKL/OPGL/TNFSF11/CD254 Western blot (WB) 6646

Anti-RANKL Antibody

11682-MM43

Application: ELISA

Clonality: MAb

Anti-RANKL Antibody

11682-R218

Specificity: Human

Application: WB

Clonality: MAb

Human RANKL/OPGL/TNFSF11/CD254 Western blot (WB) 6645

Anti-RANKL Antibody

11682-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

RANKL / OPGL / TNFSF11 / CD254 Neutralizing Antibody

11682-R001

Specificity: Human

Application: Neutralization

Clonality: MAb

Human RANKL/OPGL/TNFSF11/CD254 Blocking/Neutralization (B/N) 5574
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RANKL ELISA KIT & match antibody elias pair set ( 1 )

RANKL Matched ELISA Antibody Pair Set,Human

SEK11682

Assay Range: 234.38 pg/ml

Human RANKL/OPGL/TNFSF11/CD254 ELISA Kit Standard Curve 7070

RANKL cDNA Clone (52)

Mouse
Rat
Rhesus
Human

RANKL qPCR Primer (3)

RANKL IP Kit (1)

RANKL Lysate (6)

Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane protein which belongs to the tumor necrosis factor family. The receptor activator of nuclear factor-kappaB ligand (RANKL), its cognate receptor RANK, and its natural decoy receptor osteoprotegerin have been identified as the final effector molecules of osteoclastic bone resorption. RANK and RANKL are key regulators of bone remodeling and regulate T cell/dendritic cell communications, and lymph node formation. Moreover, RANKL and RANK are expressed in mammary gland epithelial cells and control the development of a lactating mammary gland during pregnancy. Genetically, RANKL and RANK are essential for the development and activation of osteoclasts and bone loss in response to virtually all triggers tested. Inhibition of RANKL function via the natural decoy receptor osteoprotegerin (OPG, TNFRSF11B) prevents bone loss in postmenopausal osteoporosis and cancer metastases. Importantly, RANKL appears to be the pathogenetic principle that causes bone and cartilage destruction in arthritis. RANK-RANKL signaling not only activates a variety of downstream signaling pathways required for osteoclast development, but crosstalk with other signaling pathways also fine-tunes bone homeostasis both in normal physiology and disease. In addition, RANKL and RANK have essential roles in lymph node formation, establishment of the thymic microenvironment, and development of a lactating mammary gland during pregnancy.

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