All PI3K gamma reagents are produced in house and quality controlled, including 2 PI3K gamma Antibody, 1 PI3K gamma Gene. All PI3K gamma reagents are ready to use.
PI3K gammaantibodies are validated with different applications, which are IHC-P, WB.
PI3K gammacDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each PI3K gamma of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
Kächele M, Hennige AM, Machann J, et al. Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers. Zhang Y, ed. PLoS ONE. 2015;10(12):e0144494.